Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase

Despite their low abundance, phosphoinositides play a central role in membrane traffic and signalling. PtdIns(3,4,5)P(3) and PtdIns(3,4)P(2) are uniquely important, as they promote cell growth, survival, and migration. Pathogenic organisms have developed means to subvert phosphoinositide metabolism...

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Detalles Bibliográficos
Autores principales: Walpole, Glenn F. W., Pacheco, Jonathan, Chauhan, Neha, Clark, Jonathan, Anderson, Karen E., Abbas, Yazan M., Brabant-Kirwan, Danielle, Montaño-Rendón, Fernando, Liu, Zetao, Zhu, Hongxian, Brumell, John H., Deiters, Alexander, Stephens, Len R., Hawkins, Phillip T., Hammond, Gerald R.V., Grinstein, Sergio, Fairn, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107517/
https://www.ncbi.nlm.nih.gov/pubmed/35484249
http://dx.doi.org/10.1038/s41556-022-00895-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107517/
https://www.ncbi.nlm.nih.gov/pubmed/35484249
http://dx.doi.org/10.1038/s41556-022-00895-y

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