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Novel insights into the SLC7A11-mediated ferroptosis signaling pathways in preeclampsia patients: identifying pannexin 1 and toll-like receptor 4 as innovative prospective diagnostic biomarkers

PURPOSE: Ferroptosis is associated with oxidative stress (OS) and is caused by iron-dependent lipid-peroxidative damage, but its role in PE is unclear. The aim of this study is to determine whether pannexin 1 (Panx1) and toll-like receptor 4 (TLR4) are key regulators of ferroptosis in PE. METHODS: T...

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Detalles Bibliográficos
Autores principales: El-Khalik, Sarah Ragab Abd, Ibrahim, Rowida Raafat, Ghafar, Muhammad Tarek Abdel, Shatat, Doaa, El-Deeb, Omnia Safwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107567/
https://www.ncbi.nlm.nih.gov/pubmed/35325354
http://dx.doi.org/10.1007/s10815-022-02443-x