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Development and validation of a HPLC-UV method for methadone hydrochloride quantification in a new oral solution with preservatives to be implemented in physicochemical stability studies

PURPOSE: The Pharmacy Service of the Infanta Leonor University Hospital acquires, compounds, distributes and dispenses more than 3000 L of methadone oral solution to Drug Addiction Patients Centers per year. Our purpose is to develop and validate an improved high performance liquid chromatography (H...

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Detalles Bibliográficos
Autores principales: Álvaro-Alonso, Elena Alba, Lorenzo, Mª Paz, Escobar-Rodríguez, Ismael, Aguilar-Ros, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107636/
https://www.ncbi.nlm.nih.gov/pubmed/35568901
http://dx.doi.org/10.1186/s13065-022-00827-9