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Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells

Engineered T cells have been shown to be highly effective in cancer immunotherapy, although T cell exhaustion presents a challenge for their long-term function. Additional T-cell sources must be exploited to broaden the application of engineered T cells for immune defense and reconstitution. Unlimit...

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Detalles Bibliográficos
Autores principales: Guo, Rongqun, Li, Wei, Li, Yadan, Li, Yingmei, Jiang, Zhongxing, Song, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107657/
https://www.ncbi.nlm.nih.gov/pubmed/35568954
http://dx.doi.org/10.1186/s40164-022-00285-y