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Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells
Engineered T cells have been shown to be highly effective in cancer immunotherapy, although T cell exhaustion presents a challenge for their long-term function. Additional T-cell sources must be exploited to broaden the application of engineered T cells for immune defense and reconstitution. Unlimit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107657/ https://www.ncbi.nlm.nih.gov/pubmed/35568954 http://dx.doi.org/10.1186/s40164-022-00285-y |