Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway

Liver fibrosis is a repair response process after chronic liver injury. During this process, activated hepatic stellate cells (HSCs) will migrate to the injury site and secrete extracellular matrix (ECM) to produce fibrous scars. Clearing activated HSCs may be a major strategy for the treatment of l...

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Detalles Bibliográficos
Autores principales: Sun, Sumin, Huan, Sheng, Li, Zhanghao, Yao, Yue, Su, Ying, Xia, Siwei, Wang, Shijun, Xu, Xuefen, Shao, Jiangjuan, Zhang, Zili, Zhang, Feng, Fu, Jinbo, Zheng, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107784/
https://www.ncbi.nlm.nih.gov/pubmed/35582617
http://dx.doi.org/10.7717/peerj.13376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107784/
https://www.ncbi.nlm.nih.gov/pubmed/35582617
http://dx.doi.org/10.7717/peerj.13376

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