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Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway
Liver fibrosis is a repair response process after chronic liver injury. During this process, activated hepatic stellate cells (HSCs) will migrate to the injury site and secrete extracellular matrix (ECM) to produce fibrous scars. Clearing activated HSCs may be a major strategy for the treatment of l...
Autores principales: | Sun, Sumin, Huan, Sheng, Li, Zhanghao, Yao, Yue, Su, Ying, Xia, Siwei, Wang, Shijun, Xu, Xuefen, Shao, Jiangjuan, Zhang, Zili, Zhang, Feng, Fu, Jinbo, Zheng, Shizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107784/ https://www.ncbi.nlm.nih.gov/pubmed/35582617 http://dx.doi.org/10.7717/peerj.13376 |
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