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High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1

The Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) has continuously evolved, resulting in the emergence of several variants of concern (VOCs). To study mechanisms of viral entry and potentially identify specific inhibitors, we pseudotyped lentiviral vectors with different SARS-CoV...

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Detalles Bibliográficos
Autores principales: Kuzikov, Maria, Woens, Jannis, Zaliani, Andrea, Hambach, Julia, Eden, Thomas, Fehse, Boris, Ellinger, Bernhard, Riecken, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108036/
https://www.ncbi.nlm.nih.gov/pubmed/35643072
http://dx.doi.org/10.1016/j.biopha.2022.113104