Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer

Chemotherapy is still one of the principal treatments for gastric cancer, but the clinical application of 5-FU is limited by drug resistance. Here, we demonstrate that ferroptosis triggered by STAT3 inhibition may provide a novel opportunity to explore a new effective therapeutic strategy for gastri...

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Detalles Bibliográficos
Autores principales: Ouyang, Shumin, Li, Huaxuan, Lou, Linlin, Huang, Qiuyao, Zhang, Zhenhua, Mo, Jianshan, Li, Min, Lu, Jiaye, Zhu, Kai, Chu, Yunjie, Ding, Wen, Zhu, Jianzheng, Lin, Ziyou, Zhong, Lin, Wang, Junjian, Yue, Peibin, Turkson, James, Liu, Peiqing, Wang, Yuanxiang, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108091/
https://www.ncbi.nlm.nih.gov/pubmed/35483272
http://dx.doi.org/10.1016/j.redox.2022.102317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108091/
https://www.ncbi.nlm.nih.gov/pubmed/35483272
http://dx.doi.org/10.1016/j.redox.2022.102317

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