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Targeting HMGB1-NFκb Axis and miR-21 by Glycyrrhizin: Role in Amelioration of Corneal Injury in a Mouse Model of Alkali Burn

Corneal neovascularization (CNV) is a sight-threatening condition usually associated with various inflammatory settings including chemical injury. High mobility group box 1 (HMGB1) is identified as an inflammatory alarmin in diverse tissue damage. Here, we evaluate the expression of HMGB1 and the co...

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Detalles Bibliográficos
Autores principales: Wang, Peihong, Hao, Peng, Chen, Xi, Li, Linghan, Zhou, Yongying, Zhang, Xiaohan, Zhu, Lin, Ying, Ming, Han, Ruifang, Wang, Liming, Li, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108160/
https://www.ncbi.nlm.nih.gov/pubmed/35586052
http://dx.doi.org/10.3389/fphar.2022.841267