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Mechanical Activation of the β(2)-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique Mode of Receptor Activation Involving Its N-Terminal Glycan Chains

More than 12 years have passed since the seminal observation that meningococcus, a pathogen causing epidemic meningitis in humans, occasionally associated with infectious vasculitis and septic shock, can promote the translocation of β-arrestins to the cell surface beneath bacterial colonies. The cel...

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Detalles Bibliográficos
Autores principales: Marullo, Stefano, Scott, Mark G. H., Enslen, Hervé, Coureuil, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108228/
https://www.ncbi.nlm.nih.gov/pubmed/35586623
http://dx.doi.org/10.3389/fendo.2022.883568