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NK Cells Equipped With a Chimeric Antigen Receptor That Overcomes Inhibition by HLA Class I for Adoptive Transfer of CAR-NK Cells
Dominant inhibitory receptors for HLA class I (HLA-I) endow NK cells with high intrinsic responsiveness, a process termed licensing or education, but hinder their ability to kill HLA-I(+) tumor cells. Cancer immunotherapy with adoptive transfer of NK cells must overcome inhibitory signals by such re...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108249/ https://www.ncbi.nlm.nih.gov/pubmed/35585985 http://dx.doi.org/10.3389/fimmu.2022.840844 |