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Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer

Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are associated with the establishment and progression of peritoneal metastasis. This study investigated the efficacy of replicative oncolytic adenovirus-mediated p53 gene therapy (OBP-702) against CAFs and peritoneal metastasis of ga...

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Detalles Bibliográficos
Autores principales: Ogawa, Toshihiro, Kikuchi, Satoru, Tabuchi, Motoyasu, Mitsui, Ema, Une, Yuta, Tazawa, Hiroshi, Kuroda, Shinji, Noma, Kazuhiro, Ohara, Toshiaki, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108396/
https://www.ncbi.nlm.nih.gov/pubmed/35615263
http://dx.doi.org/10.1016/j.omto.2022.04.009