N-acetylcysteine Ameliorates Vancomycin-induced Nephrotoxicity by Inhibiting Oxidative Stress and Apoptosis in the in vivo and in vitro Models

Background: Oxidative stress-related apoptosis is considered as the key mechanism implicated in the pathophysiology of nephrotoxicity with vancomycin (VCM) therapy. We evaluated the possible effects of N-acetylcysteine (NAC) on VCM-induced nephrotoxicity and the underlying mechanism. Methods: VCM-in...

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Detalles Bibliográficos
Autores principales: Yu, Ping, Luo, Jing, Song, Huahua, Qian, Tianwei, He, Xuan, Fang, Jie, Dong, Wenpei, Bian, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108398/
https://www.ncbi.nlm.nih.gov/pubmed/35582415
http://dx.doi.org/10.7150/ijms.69807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108398/
https://www.ncbi.nlm.nih.gov/pubmed/35582415
http://dx.doi.org/10.7150/ijms.69807

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