Estrogen Metabolite 2-Methoxyestradiol Attenuates Blood Pressure in Hypertensive Rats by Downregulating Angiotensin Type 1 Receptor

The therapeutic potential of 2-Methoxyestradiol (2ME2) is evident in cardiovascular disease. Our laboratory has previously demonstrated the mechanism involved in the 2ME2 regulation of angiotensin type 1 receptor (AT1R) in vitro. However, 2ME2 regulation of angiotensin receptors and its effects on b...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Ogola, Benard O., Iyer, Laxmi, Karamyan, Vardan T., Thekkumkara, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108484/
https://www.ncbi.nlm.nih.gov/pubmed/35586713
http://dx.doi.org/10.3389/fphys.2022.876777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108484/
https://www.ncbi.nlm.nih.gov/pubmed/35586713
http://dx.doi.org/10.3389/fphys.2022.876777

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