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YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation

Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets, including plasmablast, memory, and germinal center (GC) cells. B cell differentiation trajectories are determined by transcription factors, yet very few mechanisms that specifically determine early B cell f...

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Detalles Bibliográficos
Autores principales: Grenov, Amalie, Hezroni, Hadas, Lasman, Lior, Hanna, Jacob H., Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108551/
https://www.ncbi.nlm.nih.gov/pubmed/35508130
http://dx.doi.org/10.1016/j.celrep.2022.110778