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YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation
Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets, including plasmablast, memory, and germinal center (GC) cells. B cell differentiation trajectories are determined by transcription factors, yet very few mechanisms that specifically determine early B cell f...
Autores principales: | Grenov, Amalie, Hezroni, Hadas, Lasman, Lior, Hanna, Jacob H., Shulman, Ziv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108551/ https://www.ncbi.nlm.nih.gov/pubmed/35508130 http://dx.doi.org/10.1016/j.celrep.2022.110778 |
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