Cargando…

Intraperitoneal Administration of Forskolin Reverses Motor Symptoms and Loss of Midbrain Dopamine Neurons in PINK1 Knockout Rats

BACKGROUND: Parkinson’s disease (PD) is a relentless, chronic neurodegenerative disease characterized by the progressive loss of substantia nigra (SN) neurons that leads to the onset of motor and non-motor symptoms. Standard of care for PD consists of replenishing the loss of dopamine through oral a...

Descripción completa

Detalles Bibliográficos
Autores principales: Vazquez-Mayorga, Emmanuel, Grigoruta, Mariana, Dagda, Raul, Martinez, Bridget, Dagda, Ruben K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108570/
https://www.ncbi.nlm.nih.gov/pubmed/34957950
http://dx.doi.org/10.3233/JPD-213016