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Intraperitoneal Administration of Forskolin Reverses Motor Symptoms and Loss of Midbrain Dopamine Neurons in PINK1 Knockout Rats
BACKGROUND: Parkinson’s disease (PD) is a relentless, chronic neurodegenerative disease characterized by the progressive loss of substantia nigra (SN) neurons that leads to the onset of motor and non-motor symptoms. Standard of care for PD consists of replenishing the loss of dopamine through oral a...
Autores principales: | Vazquez-Mayorga, Emmanuel, Grigoruta, Mariana, Dagda, Raul, Martinez, Bridget, Dagda, Ruben K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108570/ https://www.ncbi.nlm.nih.gov/pubmed/34957950 http://dx.doi.org/10.3233/JPD-213016 |
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