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Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function

BACKGROUND: α-klotho might play a role in neurodegenerative diseases. OBJECTIVE: To determine levels of α-klotho and apoE in serum and cerebrospinal fluid (CSF) samples and their relationship with the Mini-Mental State Examination (MMSE) and Clinical Dementia Rating (CDR). METHODS: All subjects were...

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Detalles Bibliográficos
Autores principales: Kundu, Payel, Zimmerman, Benjamin, Quinn, Joseph F., Kaye, Jeffrey, Mattek, Nora, Westaway, Shawn K., Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108571/
https://www.ncbi.nlm.nih.gov/pubmed/35213382
http://dx.doi.org/10.3233/JAD-215719