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DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron  depletion

Mitophagy removes defective mitochondria via lysosomal elimination. Increased mitophagy coincides with metabolic reprogramming, yet it remains unknown whether mitophagy is a cause or consequence of such state changes. The signalling pathways that integrate with mitophagy to sustain cell and tissue i...

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Detalles Bibliográficos
Autores principales: Long, Maeve, Sanchez‐Martinez, Alvaro, Longo, Marianna, Suomi, Fumi, Stenlund, Hans, Johansson, Annika I, Ehsan, Homa, Salo, Veijo T, Montava‐Garriga, Lambert, Naddafi, Seyedehshima, Ikonen, Elina, Ganley, Ian G, Whitworth, Alexander J, McWilliams, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108618/
https://www.ncbi.nlm.nih.gov/pubmed/35411952
http://dx.doi.org/10.15252/embj.2021109390