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Targeting the Negative Feedback of Adenosine‐A2AR Metabolic Pathway by a Tailored Nanoinhibitor for Photothermal Immunotherapy

The metabolite adenosine plays an important immunosuppressive role in the tumor microenvironment (TME) through its ligation with the metabolic checkpoint adenosine 2A receptor (A2AR). Here, an adenosine‐A2AR negative feedback pathway is highlighted during photothermal‐induced immunogenic cell death...

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Detalles Bibliográficos
Autores principales: Liu, Yiqiong, Liu, Ying, Xu, Dailin, Zang, Jie, Zheng, Xiao, Zhao, Yuge, Li, Yan, He, Ruiqing, Ruan, Shuangrong, Dong, Haiqing, Gu, Jingjing, Yang, Yan, Cheng, Qian, Li, Yongyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108638/
https://www.ncbi.nlm.nih.gov/pubmed/35306759
http://dx.doi.org/10.1002/advs.202104182