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Targeting the Negative Feedback of Adenosine‐A2AR Metabolic Pathway by a Tailored Nanoinhibitor for Photothermal Immunotherapy
The metabolite adenosine plays an important immunosuppressive role in the tumor microenvironment (TME) through its ligation with the metabolic checkpoint adenosine 2A receptor (A2AR). Here, an adenosine‐A2AR negative feedback pathway is highlighted during photothermal‐induced immunogenic cell death...
Autores principales: | Liu, Yiqiong, Liu, Ying, Xu, Dailin, Zang, Jie, Zheng, Xiao, Zhao, Yuge, Li, Yan, He, Ruiqing, Ruan, Shuangrong, Dong, Haiqing, Gu, Jingjing, Yang, Yan, Cheng, Qian, Li, Yongyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108638/ https://www.ncbi.nlm.nih.gov/pubmed/35306759 http://dx.doi.org/10.1002/advs.202104182 |
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