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Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy

Long-term antiretroviral therapy (ART) in people living with HIV (PLHIV) is associated with sustained increases in CD4(+) T-cell count, but its effect on the peripheral blood T-cell repertoire has not been comprehensively evaluated. In this study, we performed serial profiling of the composition and...

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Detalles Bibliográficos
Autores principales: Towlerton, Andrea M. H., Ravishankar, Shashidhar, Coffey, David G., Puronen, Camille E., Warren, Edus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108698/
https://www.ncbi.nlm.nih.gov/pubmed/35585986
http://dx.doi.org/10.3389/fimmu.2022.879190