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MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1

Mycobacterium tuberculosis (Mtb) evades host clearance by inhibiting autophagy. MicroRNA-25 (miR-25) expression was significantly up-regulated in the lung tissues of mice infected with Bacillus Calmette-Guerin (BCG) and macrophages infected with Mtb or BCG, especially in the early stages of infectio...

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Detalles Bibliográficos
Autores principales: Dong, Wenqi, Wang, Gaoyan, Feng, Jiajia, Li, Pei, Wang, Rui, Lu, Hao, Lu, Wenjia, Wang, Chenchen, Wang, Xiangru, Chen, Huanchun, Xiang, Yaozu, Tan, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108763/
https://www.ncbi.nlm.nih.gov/pubmed/35586071
http://dx.doi.org/10.1016/j.isci.2022.104279