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Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th(17) polarization during infection
Early Th(17) responses are necessary to provide protection against Mycobacterium tuberculosis (Mtb). Mtb impedes Th(17) polarization by restricting CD40 co-stimulatory pathway on dendritic cells (DCs). We previously demonstrated that engaging CD40 on DCs increased Th(17) responses. However, the mole...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108765/ https://www.ncbi.nlm.nih.gov/pubmed/35586066 http://dx.doi.org/10.1016/j.isci.2022.104305 |