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The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins

Molecular chaperones safeguard cellular protein homeostasis and obviate proteotoxicity. In the process of aging, as chaperone networks decline, aberrant protein amyloid aggregation accumulates in a mechanism that underpins neurodegeneration, leading to pathologies such as Alzheimer’s disease and Par...

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Detalles Bibliográficos
Autores principales: Huang, Chengan, Lu, Jinxia, Ma, Xiaojuan, Qiang, Jiali, Wang, Chuchu, Liu, Cong, Fang, Yanshan, Zhang, Yaoyang, Jiang, Lin, Li, Dan, Zhang, Shengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108885/
https://www.ncbi.nlm.nih.gov/pubmed/35398355
http://dx.doi.org/10.1016/j.jbc.2022.101912