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MFG-E8 promotes tendon-bone healing by regualting macrophage efferocytosis and M2 polarization after anterior cruciate ligament reconstruction

BACKGROUND: Scar tissue formation at the tendon-bone interface caused by excessive inflammation leads to insufficient healing strength, while the phagocytic clearance of dying cells (efferocytosis) has profound consequences on macrophage polarisation and the inflammatory response. Modulating the inf...

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Detalles Bibliográficos
Autores principales: Geng, Rui, Lin, Yucheng, Ji, Mingliang, Chang, Qing, Li, Zhuang, Xu, Li, Zhang, Weituo, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109120/
https://www.ncbi.nlm.nih.gov/pubmed/35615640
http://dx.doi.org/10.1016/j.jot.2022.04.002