The Structural Features of Novel Bacterial Topoisomerase Inhibitors That Define Their Activity on Topoisomerase IV

[Image: see text] The continued emergence of bacterial resistance has created an urgent need for new and effective antibacterial agents. Bacterial type II topoisomerases, such as DNA gyrase and topoisomerase IV (topoIV), are well-validated targets for antibacterial chemotherapy. The novel bacterial...

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Detalles Bibliográficos
Autores principales: Kokot, Maja, Anderluh, Marko, Hrast, Martina, Minovski, Nikola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109137/
https://www.ncbi.nlm.nih.gov/pubmed/35503563
http://dx.doi.org/10.1021/acs.jmedchem.2c00039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109137/
https://www.ncbi.nlm.nih.gov/pubmed/35503563
http://dx.doi.org/10.1021/acs.jmedchem.2c00039

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