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An adult-stage transcriptional program for survival of serotonergic connectivity

Neurons must function for decades of life, but how these non-dividing cells are preserved is poorly understood. Using mouse serotonin (5-HT) neurons as a model, we report an adult-stage transcriptional program specialized to ensure the preservation of neuronal connectivity. We uncover a switch in Lm...

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Detalles Bibliográficos
Autores principales: Kitt, Meagan M., Tabuchi, Nobuko, Spencer, W. Clay, Robinson, Heath L., Zhang, Xinrui L., Eastman, Brent A., Lobur, Katherine J., Silver, Jerry, Mei, Lin, Deneris, Evan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109281/
https://www.ncbi.nlm.nih.gov/pubmed/35443166
http://dx.doi.org/10.1016/j.celrep.2022.110711