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Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer’s disease patient-derived induced pluripotent stem cells

The cerebral organoid (CO) model has been used in the study of various neurodegenerative diseases owing to its physiological implications. However, the CO model may only be representative of certain clinical findings in affected patients, while some features are not recapitulated. In this study, we...

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Detalles Bibliográficos
Autores principales: Lee, Ju-Hyun, Yoo, Geon, Choi, Juhyun, Park, Si-Hyung, Shin, Hyogeun, Prasad, Renuka, Lee, Yeunehee, Ahn, Mee Ryung, Cho, Il-Joo, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109296/
https://www.ncbi.nlm.nih.gov/pubmed/35578344
http://dx.doi.org/10.1186/s13041-022-00928-5