Silencing of histone deacetylase 3 suppresses the development of esophageal squamous cell carcinoma through regulation of miR-494-mediated TGIF1

BACKGROUND: Deacetylation of histones by histone deacetylase 3 (HDAC3) acts importantly in modulating apoptosis, DNA damage and cellular progression. Herein, we aimed to unravel the functional role of HDAC3 in a lethal disease, esophageal squamous cell carcinoma (ESCC). METHODS: The expression of HD...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zhang, Yuan, Lin, Zongxiang, Wu, Kai, He, Zhanfeng, Zhu, Dengyan, Zhao, Jia, Zhang, Chunyang, Fan, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109300/
https://www.ncbi.nlm.nih.gov/pubmed/35578338
http://dx.doi.org/10.1186/s12935-022-02581-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109300/
https://www.ncbi.nlm.nih.gov/pubmed/35578338
http://dx.doi.org/10.1186/s12935-022-02581-3

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