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A novel nanobody as therapeutics target for EGFR-positive colorectal cancer therapy: exploring the effects of the nanobody on SW480 cells using proteomics approach

BACKGROUND: The epidermal growth factor receptor (EGFR) overexpression is found in metastatic colorectal cancer (mCRC). Targeted molecular therapies such as monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKI) are becoming more precise, targeting specifically for cancer therapeutics. Ho...

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Detalles Bibliográficos
Autores principales: Lamtha, Thomanai, Krobthong, Sucheewin, Yingchutrakul, Yodying, Samutrtai, Pawitrabhorn, Gerner, Christopher, Tabtimmai, Lueacha, Choowongkomon, Kiattawee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109347/
https://www.ncbi.nlm.nih.gov/pubmed/35578244
http://dx.doi.org/10.1186/s12953-022-00190-6