Cargando…

A novel nanobody as therapeutics target for EGFR-positive colorectal cancer therapy: exploring the effects of the nanobody on SW480 cells using proteomics approach

BACKGROUND: The epidermal growth factor receptor (EGFR) overexpression is found in metastatic colorectal cancer (mCRC). Targeted molecular therapies such as monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKI) are becoming more precise, targeting specifically for cancer therapeutics. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lamtha, Thomanai, Krobthong, Sucheewin, Yingchutrakul, Yodying, Samutrtai, Pawitrabhorn, Gerner, Christopher, Tabtimmai, Lueacha, Choowongkomon, Kiattawee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109347/ https://www.ncbi.nlm.nih.gov/pubmed/35578244 http://dx.doi.org/10.1186/s12953-022-00190-6

Ejemplares similares

Exploring the Apoptotic-Induced Biochemical Mechanism of Traditional Thai Herb (Kerra™) Extract in HCT116 Cells Using a Label-Free Proteomics Approach
por: Siriwaseree, Jeeraprapa, et al.
Publicado: (2023)

Utilizing Quantitative Proteomics to Identify Species-Specific Protein Therapeutic Targets for the Treatment of Leishmaniasis
por: Krobthong, Sucheewin, et al.
Publicado: (2022)

Structural analysis of cannabinoids against EGFR-TK leads a novel target against EGFR-driven cell lines
por: Lamtha, Thomanai, et al.
Publicado: (2022)

Study of the Lipolysis Effect of Nanoliposome-Encapsulated Ganoderma lucidum Protein Hydrolysates on Adipocyte Cells Using Proteomics Approach
por: Krobthong, Sucheewin, et al.
Publicado: (2021)

Evaluation of potential anti-metastatic and antioxidative abilities of natural peptides derived from Tecoma stans (L.) Juss. ex Kunth in A549 cells
por: Krobthong, Sucheewin, et al.
Publicado: (2022)

Discovery of a Multifunctional Octapeptide from Lingzhi with Antioxidant and Tyrosinase Inhibitory Activity
por: Yingchutrakul, Yodying, et al.
Publicado: (2022)

Proteomics dataset for the analysis of the effects of Grammatophyllum speciosum extracts on RAW 264.7 cells
por: Yingchutrakul, Yodying, et al.
Publicado: (2023)

Proteomics and Molecular Docking Analyses Reveal the Bio-Chemical and Molecular Mechanism Underlying the Hypolipidemic Activity of Nano-Liposomal Bioactive Peptides in 3T3-L1 Adipocytes
por: Krobthong, Sucheewin, et al.
Publicado: (2023)

Potential of Arabica Coffee Beans from Northern Thailand: Exploring Antidiabetic Metabolites through Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS) Metabolomic Profiling across Diverse Postharvest Processing Techniques
por: Tantapakul, Cholpisut, et al.
Publicado: (2023)

Anti-HIV-1 reverse transcriptase property of some edible mushrooms in Asia
por: Choengpanya, Khuanjarat, et al.
Publicado: (2021)

Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies
por: Aiebchun, Thitinan, et al.
Publicado: (2021)

The Effect of the EGFR - Targeting Compound 3-[(4-Phenylpyrimidin-2-yl) Amino] Benzene-1-Sulfonamide (13f) against Cholangiocarcinoma Cell Lines
por: Samatiwat, Papavee, et al.
Publicado: (2021)

Anti-feline immunodeficiency virus reverse transcriptase properties of some medicinal and edible mushrooms
por: Seetaha, Supaphorn, et al.
Publicado: (2020)

Synchrotron Fourier Transform Infrared Microscopy Spectra in Cellular Effects of Janus Kinase Inhibitors on Myelofibrosis Cancer Cells
por: Siriwaseree, Jeeraprapa, et al.
Publicado: (2022)

Identification and Characterization of a Potential Antimicrobial Peptide Isolated from Soil Brevibacillus sp. WUL10 and Its Activity against MRSA Pathogens
por: Atipairin, Apichart, et al.
Publicado: (2022)

Identification of the Brucea javanica Constituent Brusatol as a EGFR-Tyrosine Kinase Inhibitor in a Cell-Free Assay
por: Suwattanasophon, Chonticha, et al.
Publicado: (2023)

Purification and Characterization of Novel Anti-MRSA Peptides Produced by Brevibacillus sp. SPR-20
por: Songnaka, Nuttapon, et al.
Publicado: (2022)

Generation of a Single-Chain Variable Fragment Antibody against Feline Immunoglobulin G for Biosensor Applications
por: Rasri, Natchaya, et al.
Publicado: (2023)

Proteomic Analysis Reveals Proteins Involved in the Mode of Action of β-Citronellol Identified From Citrus hystrix DC. Leaf Against Candida albicans
por: Buakaew, Watunyoo, et al.
Publicado: (2022)

Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis Improved the Anti-MRSA Activity of Brevibacillus sp. SPR20
por: Songnaka, Nuttapon, et al.
Publicado: (2023)

Biological Evaluation and Molecular Dynamics Simulation of Chalcone Derivatives as Epidermal Growth Factor-Tyrosine Kinase Inhibitors
por: Sangpheak, Kanyani, et al.
Publicado: (2019)

Discovery of JAK2/3 Inhibitors from Quinoxalinone-Containing Compounds
por: Sanachai, Kamonpan, et al.
Publicado: (2022)

Recombinant expression of nanobodies and nanobody-derived immunoreagents
por: de Marco, Ario
Publicado: (2020)

Neutralizing and Enhancing Epitopes of the SARS-CoV-2 Receptor-Binding Domain (RBD) Identified by Nanobodies
por: Kaewchim, Kanasap, et al.
Publicado: (2023)

Bioactive peptide isolated from sesame seeds inhibits cell proliferation and induces apoptosis and autophagy in leukemic cells
por: Deesrisak, Kamolchanok, et al.
Publicado: (2021)

Anti-methicillin-resistant Staphylococcus aureus and antibiofilm activity of new peptides produced by a Brevibacillus strain
por: Ogunsile, Abiodun, et al.
Publicado: (2023)

Biochemical and structural comparisons of non-nucleoside reverse transcriptase inhibitors against feline and human immunodeficiency viruses
por: Rattanabunyong, Siriluk, et al.
Publicado: (2023)

Selection, alkaline phosphatase fusion, and application of single-chain variable fragment (scFv) specific to NT-proBNP as electrochemical immunosensor for heart failure
por: Wongjard, Sureeporn, et al.
Publicado: (2023)

Differential plasma proteomes of the patients with Opisthorchiasis viverrini and cholangiocarcinoma identify a polymeric immunoglobulin receptor as a potential biomarker
por: Prasopdee, Sattrachai, et al.
Publicado: (2022)

In Silico and In Vitro Study of Janus Kinases Inhibitors from Naphthoquinones
por: Sanachai, Kamonpan, et al.
Publicado: (2023)

Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment
por: Narbona, Javier, et al.
Publicado: (2023)

Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics
por: Bannas, Peter, et al.
Publicado: (2017)

The effects of quercetin on SW480 human colon carcinoma cells: a proteomic study
por: Mouat, Michael F, et al.
Publicado: (2005)

Nanobodies that Neutralize HIV
por: Weiss, Robin A., et al.
Publicado: (2019)

The Therapeutic Potential of Nanobodies
por: Jovčevska, Ivana, et al.
Publicado: (2019)

Special Issue: Nanobody
por: Chames, Patrick, et al.
Publicado: (2020)

Safety assessment of fluorescently labeled anti-EGFR Nanobodies in healthy dogs
por: do Valle, Nayra Cristina Herreira, et al.
Publicado: (2023)

Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine–Nanobody Complex
por: Desmyter, Aline, et al.
Publicado: (2017)

Selecting Nanobodies Specific for the Epidermal Growth Factor from a Synthetic Nanobody Library
por: Serrano-Rivero, Yunier, et al.
Publicado: (2023)

Correction: Kaewchim et al. Neutralizing and Enhancing Epitopes of the SARS-CoV-2 Receptor-Binding Domain (RBD) Identified by Nanobodies. Viruses 2023, 15, 1252
por: Kaewchim, Kanasap, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t1gs5tbujlvpac1dhof1e0fta6