Regulatory analysis of single cell multiome gene expression and chromatin accessibility data with scREG

Technological development has enabled the profiling of gene expression and chromatin accessibility from the same cell. We develop scREG, a dimension reduction methodology, based on the concept of cis-regulatory potential, for single cell multiome data. This concept is further used for the constructi...

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Detalles Bibliográficos
Autores principales: Duren, Zhana, Chang, Fengge, Naqing, Fnu, Xin, Jingxue, Liu, Qiao, Wong, Wing Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109353/
https://www.ncbi.nlm.nih.gov/pubmed/35578363
http://dx.doi.org/10.1186/s13059-022-02682-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109353/
https://www.ncbi.nlm.nih.gov/pubmed/35578363
http://dx.doi.org/10.1186/s13059-022-02682-2

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