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Regulatory analysis of single cell multiome gene expression and chromatin accessibility data with scREG
Technological development has enabled the profiling of gene expression and chromatin accessibility from the same cell. We develop scREG, a dimension reduction methodology, based on the concept of cis-regulatory potential, for single cell multiome data. This concept is further used for the constructi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109353/ https://www.ncbi.nlm.nih.gov/pubmed/35578363 http://dx.doi.org/10.1186/s13059-022-02682-2 |