Therapeutic targeting of PFKFB3 and PFKFB4 in multiple myeloma cells under hypoxic conditions

The treatment of multiple myeloma (MM) patients has been dramatically changed by the introduction of new agents; however, many patients relapse. Hypoxia is a critical component of the bone-marrow microenvironment. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB) is responsible for mainta...

Descripción completa

Detalles Bibliográficos
Autores principales: Okabe, Seiichi, Tanaka, Yuko, Gotoh, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109357/
https://www.ncbi.nlm.nih.gov/pubmed/35578370
http://dx.doi.org/10.1186/s40364-022-00376-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109357/
https://www.ncbi.nlm.nih.gov/pubmed/35578370
http://dx.doi.org/10.1186/s40364-022-00376-2

Ejemplares similares