Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

BACKGROUND: Corticosteroids remain a key therapy for treating children with asthma. Patients with severe asthma are insensitive, resistant, or refractory to corticosteroids and have poorly controlled symptoms that involve airway inflammation, airflow obstruction, and frequent exacerbations. While th...

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Detalles Bibliográficos
Autores principales: Jackson, Devine, Walum, Joshua, Banerjee, Priyanka, Lewis, Brandon W., Prakash, Y. S., Sathish, Venkatachalem, Xu, Zhaohui, Britt, Rodney D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109364/
https://www.ncbi.nlm.nih.gov/pubmed/35578269
http://dx.doi.org/10.1186/s12931-022-02046-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109364/
https://www.ncbi.nlm.nih.gov/pubmed/35578269
http://dx.doi.org/10.1186/s12931-022-02046-1

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