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Immortalization effect of SV40T lentiviral vectors on canine corneal epithelial cells

BACKGROUND: Primary canine corneal epithelial cells (CCECs) easily become senescent, and cell proliferation is limited. Therefore, sampling for experimentation requires a large number of animals, which is problematic in terms of animal welfare and fails to maintain the stability of the cells for in...

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Detalles Bibliográficos
Autores principales: Guo, Long, Wang, Zhihao, Li, Jun, Li, Jianji, Cui, Luying, Dong, Junsheng, Meng, Xia, Qian, Chen, Wang, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109393/
https://www.ncbi.nlm.nih.gov/pubmed/35578336
http://dx.doi.org/10.1186/s12917-022-03288-3