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Nuclear Receptor 4A2 (NR4A2/NURR1) Regulates Autophagy and Chemoresistance in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor prognosis and chemotherapy with gemcitabine has limited effects and is associated with development of drug resistance. Treatment of Panc1 and MiaPaca2 pancreatic cancer cells with gemcitabine induced expression of the or...

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Detalles Bibliográficos
Autores principales: Zarei, Mehrdad, Shrestha, Rupesh, Johnson, Sneha, Yu, Zuhua, Karki, Keshav, Vaziri-Gohar, Ali, Epps, Jessica, Du, Heng, Suva, Larry, Zarei, Mahsa, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109828/
https://www.ncbi.nlm.nih.gov/pubmed/35582016
http://dx.doi.org/10.1158/2767-9764.CRC-21-0073