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Controlling astrocyte-mediated synaptic pruning signals for schizophrenia drug repurposing with deep graph networks

Schizophrenia is a debilitating psychiatric disorder, leading to both physical and social morbidity. Worldwide 1% of the population is struggling with the disease, with 100,000 new cases annually only in the United States. Despite its importance, the goal of finding effective treatments for schizoph...

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Detalles Bibliográficos
Autores principales: Gravina, Alessio, Wilson, Jennifer L., Bacciu, Davide, Grimes, Kevin J., Priami, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109907/
https://www.ncbi.nlm.nih.gov/pubmed/35507580
http://dx.doi.org/10.1371/journal.pcbi.1009531