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A model for isoform-level differential expression analysis using RNA-seq data without pre-specifying isoform structure
MOTIVATION: Next generation sequencing (NGS) technology has been widely used in biomedical research, particularly on those genomics-related studies. One of NGS applications is the high-throughput mRNA sequencing (RNA-seq), which is usually applied to evaluate gene expression level (i.e. copies of is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109925/ https://www.ncbi.nlm.nih.gov/pubmed/35576204 http://dx.doi.org/10.1371/journal.pone.0266162 |