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A model for isoform-level differential expression analysis using RNA-seq data without pre-specifying isoform structure

MOTIVATION: Next generation sequencing (NGS) technology has been widely used in biomedical research, particularly on those genomics-related studies. One of NGS applications is the high-throughput mRNA sequencing (RNA-seq), which is usually applied to evaluate gene expression level (i.e. copies of is...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Wang, Junying, Wu, Song, Yang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109925/
https://www.ncbi.nlm.nih.gov/pubmed/35576204
http://dx.doi.org/10.1371/journal.pone.0266162