Cargando…

A practical problem with Egger regression in Mendelian randomization

Mendelian randomization (MR) is an instrumental variable (IV) method using genetic variants such as single nucleotide polymorphisms (SNPs) as IVs to disentangle the causal relationship between an exposure and an outcome. Since any causal conclusion critically depends on the three valid IV assumption...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Zhaotong, Pan, Isaac, Pan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109933/
https://www.ncbi.nlm.nih.gov/pubmed/35507585
http://dx.doi.org/10.1371/journal.pgen.1010166