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Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse

Kv3 potassium currents mediate rapid repolarisation of action potentials (APs), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploited this to test for subunit-specific roles at the calyx...

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Detalles Bibliográficos
Autores principales: Richardson, Amy, Ciampani, Victoria, Stancu, Mihai, Bondarenko, Kseniia, Newton, Sherylanne, Steinert, Joern R, Pilati, Nadia, Graham, Bruce P, Kopp-Scheinpflug, Conny, Forsythe, Ian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110028/
https://www.ncbi.nlm.nih.gov/pubmed/35510987
http://dx.doi.org/10.7554/eLife.75219