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Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion

Transport of proteins across and into membranes is a fundamental biological process with the vast majority being conducted by the ubiquitous Sec machinery. In bacteria, this is usually achieved when the SecY-complex engages the cytosolic ATPase SecA (secretion) or translating ribosomes (insertion)....

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Detalles Bibliográficos
Autores principales: Allen, William J, Corey, Robin A, Watkins, Daniel W, Oliveira, A Sofia F, Hards, Kiel, Cook, Gregory M, Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110029/
https://www.ncbi.nlm.nih.gov/pubmed/35486093
http://dx.doi.org/10.7554/eLife.77586