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Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion
Transport of proteins across and into membranes is a fundamental biological process with the vast majority being conducted by the ubiquitous Sec machinery. In bacteria, this is usually achieved when the SecY-complex engages the cytosolic ATPase SecA (secretion) or translating ribosomes (insertion)....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110029/ https://www.ncbi.nlm.nih.gov/pubmed/35486093 http://dx.doi.org/10.7554/eLife.77586 |