Methylation of dual-specificity phosphatase 4 controls cell differentiation

Mitogen-activated protein kinases (MAPKs) are inactivated by dual-specificity phosphatases (DUSPs), the activities of which are tightly regulated during cell differentiation. Using knockdown screening and single-cell transcriptional analysis, we demonstrate that DUSP4 is the phosphatase that specifi...

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Detalles Bibliográficos
Autores principales: Su, Hairui, Jiang, Ming, Senevirathne, Chamara, Aluri, Srinivas, Zhang, Tuo, Guo, Han, Xavier-Ferrucio, Juliana, Jin, Shuiling, Tran, Ngoc-Tung, Liu, Szu-Mam, Sun, Chiao-Wang, Zhu, Yongxia, Zhao, Qing, Chen, Yuling, Cable, LouAnn, Shen, Yudao, Liu, Jing, Qu, Cheng-Kui, Han, Xiaosi, Klug, Christopher A., Bhatia, Ravi, Chen, Yabing, Nimer, Stephen D., Zheng, Y. George, Iancu-Rubin, Camelia, Jin, Jian, Deng, Haiteng, Krause, Diane S., Xiang, Jenny, Verma, Amit, Luo, Minkui, Zhao, Xinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110119/
https://www.ncbi.nlm.nih.gov/pubmed/34320342
http://dx.doi.org/10.1016/j.celrep.2021.109421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110119/
https://www.ncbi.nlm.nih.gov/pubmed/34320342
http://dx.doi.org/10.1016/j.celrep.2021.109421

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