Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms

Estradiol action is mediated by estrogen receptors (ERs), a and ß. Estradiol binding initiates ER-mediated transcription and ER degradation, the latter of which occurs via the ubiquitin-proteasome pathway. Inhibition of proteasome activity prevents estradiol-induced ERα degradation and transactivati...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Houng-Wei, Lin, Vicky Y., Shupnik, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110234/
https://www.ncbi.nlm.nih.gov/pubmed/35586275
http://dx.doi.org/10.1155/2022/7690166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110234/
https://www.ncbi.nlm.nih.gov/pubmed/35586275
http://dx.doi.org/10.1155/2022/7690166

Ejemplares similares