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Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms

Estradiol action is mediated by estrogen receptors (ERs), a and ß. Estradiol binding initiates ER-mediated transcription and ER degradation, the latter of which occurs via the ubiquitin-proteasome pathway. Inhibition of proteasome activity prevents estradiol-induced ERα degradation and transactivati...

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Detalles Bibliográficos
Autores principales:	Tsai, Houng-Wei, Lin, Vicky Y., Shupnik, Margaret A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110234/ https://www.ncbi.nlm.nih.gov/pubmed/35586275 http://dx.doi.org/10.1155/2022/7690166

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