LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells

Several studies have indicated that mutations of LARS2 are associated with premature ovarian insufficiency (POI). However, the pathogenic mechanism of LARS2 in POI has not been reported yet. In the present study, the expression levels of LARS2 and E2F1 in granulosa cells (GCs) of POI patients were e...

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Detalles Bibliográficos
Autores principales: Feng, Shujun, Wan, Shan, Liu, Shuangying, Wang, Wei, Tang, Minyue, Bai, Long, Zhu, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110257/
https://www.ncbi.nlm.nih.gov/pubmed/35585880
http://dx.doi.org/10.1155/2022/5501346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110257/
https://www.ncbi.nlm.nih.gov/pubmed/35585880
http://dx.doi.org/10.1155/2022/5501346

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