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Identifiability analysis for models of the translation kinetics after mRNA transfection

Mechanistic models are a powerful tool to gain insights into biological processes. The parameters of such models, e.g. kinetic rate constants, usually cannot be measured directly but need to be inferred from experimental data. In this article, we study dynamical models of the translation kinetics af...

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Detalles Bibliográficos
Autores principales: Pieschner, Susanne, Hasenauer, Jan, Fuchs, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110294/
https://www.ncbi.nlm.nih.gov/pubmed/35577967
http://dx.doi.org/10.1007/s00285-022-01739-x