Potential drug discovery for COVID-19 treatment targeting Cathepsin L using a deep learning-based strategy

Cathepsin L (CTSL), a cysteine protease that can cleave and activate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, could be a promising therapeutic target for coronavirus disease 2019 (COVID-19). However, there is still no clinically available CTSL inhibitor that ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Wei-Li, Li, Qi, Sun, Jing, Huat Tan, Sia, Tang, Yan-Hong, Zhao, Miao-Miao, Li, Yu-Yang, Cao, Xi, Zhao, Jin-Cun, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110316/
https://www.ncbi.nlm.nih.gov/pubmed/35602976
http://dx.doi.org/10.1016/j.csbj.2022.05.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110316/
https://www.ncbi.nlm.nih.gov/pubmed/35602976
http://dx.doi.org/10.1016/j.csbj.2022.05.023

Ejemplares similares